Bryce Harper home run celebration

May 14, 2022; Los Angeles, California, USA; Philadelphia Phillies right fielder Bryce Harper (3) and first baseman Rhys Hoskins (17) celebrate after a home run against the Los Angeles Dodgers during the third inning at Dodger Stadium. Mandatory Credit: Jonathan Hui-USA TODAY Sports

  • The Padres vs Phillies odds favor Philadelphia as -120 moneyline favorites on Thursday (May 19, 1:05 pm ET)
  • San Diego will send Yu Darvish 3-1, 4.62 ERA) to the mound, while Philly will counter with Kyle Gibson (3-1, 4.10 ERA)
  • Read below for the Padres vs Phillies odds, analysis and betting prediction

San Diego and Philadelphia will close out a three-game series on Thursday afternoon in the city of Brotherly Love. The Phillies rebounded from a 3-0 defeat in the series opener on Tuesday, posting a 3-0 victory of their own on Wednesday.

The win snapped a three-game losing streak for Philadelphia, and oddsmakers are expecting them to keep the momentum going in the series finale.

Padres vs Phillies Odds

Team Moneyline Runline Total
San Diego Padres +100 +1.5 (-180) O 8.0 (-115)
Philadelphia Phillies -120 -1.5 (+155) U 8.0 (-105)

Odds as of May 18th at Caesars Sportsbook.



The Phillies opened up as -120 moneyline favorites, in a contest that features a total of 8 runs. First pitch is scheduled for 1:05pm ET at Citizens Bank Park in Philadelphia, PA, with cloudy skies and 76 degree temperatures in the forecast.

San Diego vs Philadelphia Pitchers

The Padres, a top-10 contender in the World Series odds, will give the ball to veteran Yu Darvish. The 35-year-old is coming off his worst start of the season, where he surrendered nine hits and five runs to Atlanta.

Darvish had pitched very well in his previous three starts, a stretch that includes 6 innings of shutout ball against the Dodgers.

He’s 1-1 in five career starts against the Phillies, and has limited the current Philadelphia roster to a .244 slugging percentage and .435 OPS over 74 at-bats

Darvish vs Gibson

3-1 Record 3-1
4.62 ERA 4.10
1.18 WHIP 1.21
.235 OBA .232
2.9 SO/W Ratio 2.3

The Phillies will turn to Kyle Gibson, who’s also coming off his worst outing of the year. Gibson allowed eight hits and six runs over 3.2 innings last week versus the Dodgers, which snapped a stretch of three solid starts.

He’s 2-0 in three career outings against the Padres, holding the San Diego roster to a .317 slugging percentage and .634 OPS.

Padres vs Phillies Betting Analysis

The San Diego lineup has actually been quite disappointing despite their 23-14 record. They rank ninth in runs, but bottom-11 in MLB in batting average, slugging and OPS. Things would be a lot worse if not for the play of Manny Machado and Eric Hosmer.

The duo rank second and third in MLB in batting average, while Machado is currently the favorite in the NL MVP odds. San Diego’s lineup will look much different once All-Star Fernando Tatis returns, but he’s still recovering from offseason wrist surgery.

Philadelphia meanwhile, should get reigning MVP Bryce Harper back on Thursday. Harper has missed the last three games after getting a PRP injection for his injured right elbow, and the Phillies have averaged only 2.3 runs per outing in his absence.

Before sitting out the early part of this week, Harper ranked first in MLB in home runs, slugging, runs and doubles, and second in OPS and RBI. The rest of the Philadelphia lineup has been a mixed bag, but fuelled by Harper, they still rank top-six in runs, batting average, slugging and OPS.

SD vs PHI Last 10 Meetings

Date Away Team Home Team Score
5/18/22 Padres Phillies PHI, 3-0
5/17/22 Padres Phillies SD, 3-0
8/22/21 Phillies Padres PHI, 7-4
8/21/21 Phillies Padres SD, 4-3
8/20/21 Phillies Padres PHI, 4-3
7/4/21 Padres Phillies SD, 11-1
7/3/21 Padres Phillies PHI, 3-2
7/2/21 Padres Phillies PHI, 4-3
8/17/19 Padres Phillies PHI, 3-2
8/16/19 Padres Phillies PHI, 5-3

Padres vs Phillies Pick

With Harper likely coming back and Gibson and Darvish fresh off horrible outings, there’s plenty of reasons to like the over in this matchup.

Also working in favor of the over is an underwhelming bullpen for both clubs. San Diego and Philadelphia relievers each rank in the bottom-nine in MLB in ERA and strand rate, which has led to a number of high scoring games.

Twelve of the Padres 20 road games have exceeded the total, while the over is 19-16-2 in Phillies contests this season. Three of Gibson’s last five starts have produced double-digit runs, while two of Darvish’s last three outings have as well.

Pick: Over 8.0 Runs (-115)


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