Pittsburgh Pirates starting pitcher JT Brubaker throwing a pitch

Apr 30, 2022; Pittsburgh, Pennsylvania, USA; Pittsburgh Pirates starting pitcher JT Brubaker (34) delivers against the San Diego Padres during the first inning at PNC Park. Mandatory Credit: Charles LeClaire-USA TODAY Sports

  • The Pirates are -129 road favorites over the Reds on Friday night
  • JT Brubaker (0-2, 6.20) for Pittsburgh against Connor Overton (0-0, 1.69)
  • A look at the Pirates vs Reds odds and matchup is below with a prediction

The Cincinnati Reds will try to break their lengthy losing streak when they host the Pittsburgh Pirates at 6:40 p.m. ET Friday at Great American Ball Park in the opener of a four-game series.

The Pirates (10-14, 5-7 road) were off Thursday after splitting a doubleheader with the Tigers on Wednesday in Detroit. Pittsburgh lost the first game 3-2 but took the nightcap 7-2 for a split. The Pirates have lost six of their last eight games.

The Reds (3-22, 1-7 home) had their losing streak reach nine game Thursday as they were defeated by the Brewers 10-5 in Milwaukee. Cincinnati has dropped 20 of its last 21 games.

Pirates vs Reds Odds

Team Moneyline Runline Total
Pittsburgh Pirates -129 -1.5 (+123) Over 8.5 (-104)
Cincinnati Reds +110 +1.5 (-155) Under 8.5 (-115)

Odds as of May 5th at Barstool Sportsbook.


The Pirates are -129 favorites on the moneyline, giving them an implied win probability of 56.33%.

The game could be delayed as there is an 80% chance of showers and possibly thunderstorms. The low temperature will be 54 degrees with wind from the north at 6-9 mph.

Both teams are major longshots to win it all this season. The Reds’ World Series odds are +10000 and the Pirates’ are a whopping +40000.

Pittsburgh vs Cincinnati Probable Pitchers

JT Brubaker (0-2, 6.20) will start for the Pirates against rookie Connor Overton (0-0, 1.69). Both will be pitching on five days of rest.

Brubaker vs Overton

0-2 Record 0-0
6.20 ERA 1.69
4.26 xERA 2.75
1.52 WHIP 0.94
1.75 SO/W 1.50

Brubaker has yet to win in five starts this season and had a no-decision in his previous start Saturday against the visiting San Diego Padres. Brubaker worked five innings and gave up three runs and five hits while striking out four and walking one.

The Reds have proven to be a tough matchup for Brubaker. He is 1-2 with a 4.87 ERA in four career starts against them and has an 0-2 record and 6.28 ERA in three starts at Great American Ball Park.

Brubaker is 0-2 with a 5.73 ERA in three starts on the road in 2022 and 0-1 with a 5.65 ERA in three outings at night.

Overton will be making his second start after pitching well in his Reds’ debut last Saturday. Facing the Rockies in Colorado, Overton allowed one run and three hits in 5.1 innings in a no-decision with three walks and two strikeouts.

Overton made two starts and two relief appearances with Triple-A Louisville to start the season. He had a 2-1 record and 2.84 ERA.

Overton has never faced the Pirates, though he did pitch in five games (three starts) for them last year.

Pirates vs Reds Betting Outlook

Third baseman Ke’Bryan Hayes’ error cost the Pirates in Game 1 of Wednesday’s doubleheader as it allowed two runs to score.

However, the Pirates scored twice in the seventh inning in the second game to pull ahead 3-2 then pulled away. Brian Reynolds doubled in the seventh. After the tying run scored on a wild pitch, Daniel Vogelbach hit a sacrifice fly to plate Reynolds with the go-ahead run.

Vogelbach added a two-run home run in the ninth inning after Ben Gamel stroked an RBI single for his fifth hit of the twinbill.

Tyler Stephenson homered and drove in two runs for the Reds Thursday, but they could not overcome the Brewers’ six home runs.

This is the first meeting between the teams in 2022 after the Reds won the season series 13-6 last year. Mike Moustakas hit .378 (14 for 37) with four doubles and two home runs for the Reds.

Pirates vs Reds Last 10 Meetings

Date Home Team Away Team Score
10/3/21 Pirates Reds CIN, 6-3
10/2/21 Pirates Reds PIT, 8-6
10/1/21 Pirates Reds PIT, 9-2
9/27/21 Reds Pirates CIN, 13-1
9/21/21 Reds Pirates PIT, 6-2
9/20/21 Reds Pirates CIN, 9-5
9/16/21 Pirates Reds CIN, 1-0
9/15/21 Pirates Reds PIT, 5-4
9/14/21 Pirates Reds PIT, 6-5
8/8/21 Reds Pirates CIN, 3-2

Pirates vs Reds Prediction

Though the Pirates haven’t been playing good ball over the last week and Brubaker has yet to win a game, the only way to go in any game involving Cincinnati at this point is to fade the Reds.

Pick: Pirates ML (-129)

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