One of the weekend’s best soccer matchups happens in Serie A when Inter Milano hosts AS Roma. Inter is a big favorite to hand Roma a loss. Then on Sunday, AC Milan takes on Lazio Rome and then on Monday, Sassuolo hosts Juventus. Keep reading for Serie A odds, analysis, and free picks for six of this weekend’s best Serie A matches. 

Top Italy Serie A Matchday 33 Games to Wager On (April 23rd – 25th)

Atalanta BC -1 -129 vs Venezia FC +1 +102

  • When: Saturday, April 23 at 9:00 am ET

Both teams are a mess. Home team Venezia has lost 5 straight. Road squad Atalanta has lost 4-of-5 with a draw.

Atalanta’s draw happened versus Bundesliga power RB Leipzig in a Europa League game. That might be why Atalanta is a handicap favorite. Venezia’s odds definitely attract. But one thing to keep in mind is that Atalanta has won the last couple of head-to-head matches by a combined 6 goals to 0. Laying the goal makes sense. 

Soccer Pick: Atalanta 

AS Roma +400 vs Inter Milano -161

  • When: Saturday, April 23 at 12:00 pm ET

On Saturday, Inter offers fair odds to beat rival Roma. The home chalk has won 4-of-5 with a draw. The draw happened against Fiorentina.

Milano’s victories include beating Juventus 1-0. In their last match, Inter bested AC Milan 3-0. Roma is in decent form. But Milano has won the last 2 head-to-head matches by 2 goals and by 3 goals. AS Roma will be lucky to get a goal in this one.  

Soccer Pick: Inter Milano  

ACF Fiorentina -1 +107 vs US Salernitana +1 -136

  • When: Sunday, April 24 at 6:30 am ET

Salernitana doesn’t host Fiorentina playing their best. The home team in this fell to Udinese by a goal in their last head-to-head. In their last 5, Salernitana has won a single match, 2-1 over Sassuolo.

Fiorentina fell by a couple of goals to Juventus on April 20. Not counting the Coppa Italia match, Fiorentina has played well, drawing with Inter in late March and beating Empoli, Venezia, and Napoli in April. The road team won the last head-to-head by a 4-0 score. Fiorentina to cover is the play.  

Soccer Pick: ACF Fiorentina  

SSC Napoli -166 vs Empoli FC +400

  • When: Sunday, April 24 at 9:00 am ET

On April 16, in Empoli’s last, Udinese blasted the road team in this 4-1. Based on that match, Empoli has no shot of beating Napoli.

But Napoli’s form isn’t great. The road favorite has a loss and a draw in their last couple of games. Napoli should win. Empoli, though, may be catching the chalk at the perfect time and this does happen on the underdog’s pitch. 

Soccer Pick: Empoli FC  

AC Milan +137 vs Lazio Rome +190

  • When: Sunday, April 24 at 2:45 pm ET

Both teams are in decent enough form to win this. AC Milan will be looking for the bounce back after suffering a 3-0 loss to Inter in their last

Lazio has won 3-of-5 with a draw and a loss. The loss happened back on March 20. Since losing to Roma, Lazio has picked it up big time. The road team shouldn’t offer such healthy odds, which is why they’re the best play in this game. 

Soccer Pick: Lazio Rome  

Juventus Turin -126 vs Sassuolo Calcio +310

  • When: Monday, April 25 at 2:45 pm ET

Since an 0-1 loss to Inter on April 3, Juve has won twice and drawn once. Sassuolo shows 2 losses, a draw, and 2 wins in their last 5.

The home underdog fell in the last head-to-head. But Sassuolo beat Juventus in the contest before last. At the over 3-to-1 odds, the home squad is worth a look. 

Soccer Pick: Sassuolo Calcio



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