May 14, 2022; Chicago, Illinois, USA; Chicago White Sox shortstop Tim Anderson (7) throws to first base after forcing New York Yankees third baseman Josh Donaldson (28) out at second during the sixth inning at Guaranteed Rate Field. Mandatory Credit: Matt Marton-USA TODAY Sports
- The New York Yankees are -220 home favorites over the Chicago White Sox in an American League afternoon game slated for Saturday, May 21
- Friday’s series opener was postponed due to rain. It will be made up as part of a doubleheader on Sunday, May 22
- All of the White Sox vs Yankees odds, picks, predictions and best bets are analyzed in the story below
The New York Yankees (28-10, 14-4 home) are rolling, while the Chicago White Sox (19-19, 10-9 road) continue to find themselves scuffling as the two teams move into the final third of the month of May.
New York is 21-4 over the past 25 games. Chicago continues to tread water. The ChiSox are 6-6 through their past 12 games.
It’s the Yankees that oddsmakers are expecting to continue winning when these two clubs take the diamond on Saturday. The MLB betting lines are showing that New York is a solid -220 home favorite. The Yanks are 10-1 straight up in their last 11 home games.
White Sox vs Yankees Odds
| Team | Moneyline | Runline | Total |
|---|---|---|---|
| Chicago White Sox | +190 | OFF | O 9 (-115) |
| New York Yankees | -220 | OFF | U 9 (-105) |
Odds as of May 20th at Caesars Sportsbook.
The first pitch is slated to be thrown at 1:05pm ET on Saturday, May 21 at Yankee Stadium. While Friday’s series opener was rained out, Saturday’s forecast is calling for clear skies, 11 mph wind and a temperature of 91 degrees.
While a solid straight up play, the Yankees are just 20-18 against the runline and 9-9 at home. The White Sox are 18-20 ATR and 11-8 ATR away from home.
Across the leading sportsbooks, New York is the -220 odds-on favorite to win the division in the AL East odds. Despite their struggles, the White Sox remain the -170 odds-on chalk to emerge with the AL Central flag.
Southpaw Showdown In The Bronx
In this battle of lefties, it’s the White Sox who are sending a former Cy Young Award winner to the hill. But it’s the Yankees who are favored.
Dallas Keuchel won the AL Cy Young Award with the Houston Astros in 2015. However, this year, he’s looking nothing like that pitcher. Keuchel’s ERA (5.54) is a career high and his strikeouts/walks ratio (1.07) is a career low. His 1.96 WHIP is Keuchel’s worst since his 2012 rookie campaign.
Keuchel Saturday
Cueto Game 1 Sunday
Kopech Game 2 Sunday— Daryl Van Schouwen (@CST_soxvan) May 20, 2022
Keuchel did work five shutout innings against the Yankees in his last start on May 14. He’s 1-0 with a 1.64 ERA over his past two starts. Keuchel is 1-1 with an 11.57 ERA in two road starts.
He’s 4-4 with a 2.06 ERA in 10 career starts against the Yanks. At Yankee Stadium, Keuchel is 3-2 with a 2.43 ERA in six starts.
Keuchel vs Cortes
| 2-3 | Record | 2-1 |
| 5.54 | ERA | 1.35 |
| 3.98 | xERA | 2.17 |
| 1.96 | WHIP | 0.85 |
| 1.07 | SO/W Ratio | 4.45 |
New York lefty Nestor Cortes is 2-1 over his last four starts. He got the win over the White Sox in May 15, allowing three hits and one earned run on a solo homer over eight innings.
Cortes has worked into the eighth inning in each of his last two starts, allowing just that one earned run over the course of 15.1 innings pitched.
Nestor Cortes has been that guy this year for the Yankees pic.twitter.com/u9lAcmOBMq
— Bronx Central (@BronxCentral) May 16, 2022
In his second stint with the Bronx Bombers, Cortes is 9-5 over his career with the Yanks. He’s 3-0 in three career appearances against the White Sox, two of them starts. His ERA over 19 innings of work when facing the ChiSox is 1.89.
Batting Average vs Starting Pitchers
| Yankees Batters | Batting Average vs Keuchel | White Sox Batters | Batting Average vs Cortes |
|---|---|---|---|
| Josh Donaldson | .237 | Jose Abreu | .286 |
| Joey Gallo | .200 | Tim Anderson | ..375 |
| Marwin Gonzalez | .000 | Adam Engel | .333 |
| Aaron Hicks | .125 | Leury Garcia | .200 |
| Kyle Higashioka | .000 | Yasmani Grandal | .000 |
| Aaron Judge | .308 | Josh Harrison | .000 |
| Isiah Kiner-Falefa | .385 | Reese McGuire | .250 |
| DJ Lemahieu | .250 | Yoan Moncada | .333 |
| Anthony Rizzo | .167 | AJ Pollock | .000 |
| Ginacarlo Stanton | .545 | Luis Robert | .167 |
| Gleyber Torres | .400 | Gavin Sheets | .000 |
| Jose Trevino | .000 | Andrew Vaughn | .167 |
Yankees DH Giancarlo Stanton is 6-for-11 (.545) with two homers and 5 RBI off of Keuchel. Gleyber Torres is 4-for-10 (.400) off of Keuchel with two RBI.
Both Isiah Kiner-Falefa (5-for-13, 385) and Aaron Judge (4-for-13, .308) have also hit Keuchel well. Josh Donaldson has taken Keuchel deep twice.
#gamblingtwitter
Dallas Keuchel .409 v LHH
Dallas Keuchel xFIP 6.2 v LHH
Dallas Keuchel .300 v RHH
Dallas Keuchel xFIP 4.49 v RHHNYY vs LHP
Aaron Judge ISO .378
Gleyber Torres ISO .303
Anthony Rizzo ISO .289
Giancarlo Stanton ISO .244
DJ LeMahieu wRC+ 205
Aaron Judge wRC+ 185— Scott Jackson (@EsplorareTravel) May 21, 2022
For the White Sox, Tim Anderson is 3-for-8 (.375) against Cortes. Adam Engel and Yoan Moncada are both 1-for-3 (.333). Engels’ hit was a solo homer. Andrew Vaughan also hit a solo shot off Cortes.
White Sox vs Yankees Prediction
Keuchel traditionally pitches well against the Yankees. Cortes currently is pitching well against everybody.
We need more of these !!! https://t.co/KgEF28aFv6
— Nestor Cortes (@Cortes_1210) May 17, 2022
Go with the home team on this one.
Pick: New york Yankees ML (-220)
An industry veteran, Bob literally taught the course on the history of sports at Elder College. He has worked as a Sports Columnist for Postmedia, appeared as a guest on several radio stations, was the Vice President of the Society For International Hockey Research in Ontario, and written 25 books.